Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells-Reference-Cited by-同舟云学术

Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells

Published:2018-07-27 Issue:8 Volume:50 Page:1122-1131
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Thomsen Soren K.^ORCID,Raimondo Anne,Hastoy Benoit^ORCID,Sengupta Shahana^ORCID,Dai Xiao-Qing,Bautista Austin,Censin Jenny^ORCID,Payne Anthony J.,Umapathysivam Mahesh M.,Spigelman Aliya F.,Barrett Amy,Groves Christopher J.,Beer Nicola L.,Manning Fox Jocelyn E.,McCarthy Mark I.^ORCID,Clark Anne,Mahajan Anubha^ORCID,Rorsman Patrik,MacDonald Patrick E.,Gloyn Anna L.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/s41588-018-0173-1.pdf

Reference68 articles.

1. Dimas, A. S. et al. Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Diabetes 63, 2158–2171 (2014).

2. Morris, A. P. et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat. Genet. 44, 981–990 (2012).

3. Fuchsberger, C. et al. The genetic architecture of type 2 diabetes. Nature 536, 41–47 (2016).

4. Mahajan, A. et al. Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. Nat. Genet. 50, 559–571 (2018).

5. Thomsen, S. K. & Gloyn, A. L. Human genetics as a model for target validation: finding new therapies for diabetes. Diabetologia 60, 960–970 (2017).

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