Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification
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Published:2023-09-28
Issue:10
Volume:55
Page:1651-1664
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Kavousi MaryamORCID, Bos Maxime M., Barnes Hanna J., Lino Cardenas Christian L.ORCID, Wong Doris, Lu HaojieORCID, Hodonsky Chani J.ORCID, Landsmeer Lennart P. L., Turner Adam W., Kho Minjung, Hasbani Natalie R., de Vries Paul S., Bowden Donald W., Chopade Sandesh, Deelen JorisORCID, Benavente Ernest Diez, Guo XiuqingORCID, Hofer Edith, Hwang Shih-Jen, Lutz Sharon M., Lyytikäinen Leo-PekkaORCID, Slenders Lotte, Smith Albert V.ORCID, Stanislawski Maggie A.ORCID, van Setten JessicaORCID, Wong Quenna, Yanek Lisa R.ORCID, Becker Diane M., Beekman MarianORCID, Budoff Matthew J.ORCID, Feitosa Mary F.ORCID, Finan ChrisORCID, Hilliard Austin T., Kardia Sharon L. R., Kovacic Jason C., Kral Brian G.ORCID, Langefeld Carl D.ORCID, Launer Lenore J.ORCID, Malik Shaista, Hoesein Firdaus A. A. Mohamed, Mokry MichalORCID, Schmidt Reinhold, Smith Jennifer A.ORCID, Taylor Kent D., Terry James G., van der Grond Jeroen, van Meurs Joyce, Vliegenthart Rozemarijn, Xu Jianzhao, Young Kendra A., Zilhão Nuno R., Zweiker Robert, Assimes Themistocles L.ORCID, Becker Lewis C., Bos Daniel, Carr J. JeffreyORCID, Cupples L. Adrienne, de Kleijn Dominique P. v., de Winther Menno, den Ruijter Hester M., Fornage MyriamORCID, Freedman Barry I.ORCID, Gudnason VilmundurORCID, Hingorani Aroon D.ORCID, Hokanson John E., Ikram M. ArfanORCID, Išgum IvanaORCID, Jacobs David R.ORCID, Kähönen Mika, Lange Leslie A., Lehtimäki Terho, Pasterkamp GerardORCID, Raitakari Olli T., Schmidt HelenaORCID, Slagboom P. ElineORCID, Uitterlinden André G.ORCID, Vernooij Meike W., Bis Joshua C.ORCID, Franceschini Nora, Psaty Bruce M.ORCID, Post Wendy S., Rotter Jerome I.ORCID, Björkegren Johan L. M.ORCID, O’Donnell Christopher J., Bielak Lawrence F.ORCID, Peyser Patricia A.ORCID, Malhotra RajeevORCID, van der Laan Sander W.ORCID, Miller Clint L.ORCID
Publisher
Springer Science and Business Media LLC
Reference109 articles.
1. Timmis, A. et al. European Society of Cardiology: Cardiovascular Disease Statistics 2017. Eur. Heart J. 39, 508–579 (2018). 2. Tsao, C. W. et al. Heart Disease and Stroke Statistics—2022 Update: a report from the American Heart Association. Circulation 145, e153–e639 (2022). 3. Libby, P., Ridker, P. M. & Hansson, G. K. Progress and challenges in translating the biology of atherosclerosis. Nature 473, 317–325 (2011). 4. Baber, U. et al. Prevalence, impact, and predictive value of detecting subclinical coronary and carotid atherosclerosis in asymptomatic adults: the BioImage study. J. Am. Coll. Cardiol. 65, 1065–1074 (2015). 5. Polonsky, T. S. et al. Coronary artery calcium score and risk classification for coronary heart disease prediction. JAMA 303, 1610–1616 (2010).
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