Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection-Reference-Cited by-同舟云学术

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

Published:2018-02-26 Issue:3 Volume:50 Page:381-389
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Pardiñas Antonio F.^ORCID, ,Holmans Peter,Pocklington Andrew J.,Escott-Price Valentina,Ripke Stephan^ORCID,Carrera Noa,Legge Sophie E.^ORCID,Bishop Sophie,Cameron Darren^ORCID,Hamshere Marian L.,Han Jun,Hubbard Leon,Lynham Amy^ORCID,Mantripragada Kiran,Rees Elliott,MacCabe James H.^ORCID,McCarroll Steven A.,Baune Bernhard T.^ORCID,Breen Gerome^ORCID,Byrne Enda M.^ORCID,Dannlowski Udo,Eley Thalia C.^ORCID,Hayward Caroline^ORCID,Martin Nicholas G.,McIntosh Andrew M.^ORCID,Plomin Robert,Porteous David J.^ORCID,Wray Naomi R.^ORCID,Caballero Armando,Geschwind Daniel H.,Huckins Laura M.^ORCID,Ruderfer Douglas M.,Santiago Enrique^ORCID,Sklar Pamela,Stahl Eli A.,Won Hyejung^ORCID,Agerbo Esben^ORCID,Als Thomas D.^ORCID,Andreassen Ole A.,Bækvad-Hansen Marie,Mortensen Preben Bo,Pedersen Carsten Bøcker,Børglum Anders D.,Bybjerg-Grauholm Jonas^ORCID,Djurovic Srdjan,Durmishi Naser,Pedersen Marianne Giørtz,Golimbet Vera,Grove Jakob^ORCID,Hougaard David M.^ORCID,Mattheisen Manuel,Molden Espen^ORCID,Mors Ole,Nordentoft Merete,Pejovic-Milovancevic Milica,Sigurdsson Engilbert^ORCID,Silagadze Teimuraz,Hansen Christine Søholm^ORCID,Stefansson Kari,Stefansson Hreinn,Steinberg Stacy,Tosato Sarah^ORCID,Werge Thomas,Collier David A.^ORCID,Rujescu Dan,Kirov George,Owen Michael J.^ORCID,O’Donovan Michael C.^ORCID,Walters James T. R.^ORCID,

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/s41588-018-0059-2.pdf

Reference105 articles.

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2. Thornicroft, G. Physical health disparities and mental illness: the scandal of premature mortality. Br. J. Psychiatry 199, 441–442 (2011).

3. Olfson, M., Gerhard, T., Huang, C., Crystal, S. & Stroup, T. S. Premature mortality among adults with schizophrenia in the United States. JAMA Psychiatry 72, 1172–1181 (2015).

4. Morgan, C. et al. Reappraising the long-term course and outcome of psychotic disorders: the AESOP-10 study. Psychol. Med. 44, 2713–2726 (2014).

5. Schizophrenia Working Group of the Psychiatric Genomics Consortium. Biological insights from 108 schizophrenia-associated genetic loci. Nature 511, 421–427 (2014).

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