Shared genetic effects on chromatin and gene expression indicate a role for enhancer priming in immune response
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics
Link
http://www.nature.com/articles/s41588-018-0046-7.pdf
Reference75 articles.
1. Li, Y. et al. Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi. Nat. Med. 22, 952–960 (2016).
2. Barreiro, L. B. et al. Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosisinfection. Proc. Natl Acad. Sci. USA 109, 1204–1209 (2012).
3. Fairfax, B. P. et al. Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression. Science 343, 1246949 (2014).
4. Kim, S. et al. Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes. Nat. Commun. 5, 5236 (2014).
5. Lee, M. N. et al. Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science 343, 1246980 (2014).
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