The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes-Reference-Cited by-全球学者库

The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes

Published:2018-08-24 Issue:10 Volume:28 Page:981-995
ISSN:1001-0602
Container-title:Cell Research
language:en
Short-container-title:Cell Res

Author:

Chen Juan,Cai Zhaokui,Bai Meizhu,Yu Xiaohua,Zhang Chao,Cao Changchang,Hu Xihao,Wang Lei,Su Ruibao,Wang Di,Wang Lei,Yao Yingpeng,Ye Rong,Hou Baidong,Yu Yang,Yu Shuyang,Li Jinsong,Xue Yuanchao

Funder

Chinese Ministry of Science and Technology | Department of S and T for Social Development

Chinese Academy of Sciences

National Natural Science Foundation of China

Chinese Academy of Sciences Key Project

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/s41422-018-0076-9.pdf

Reference67 articles.

1. Tonegawa, S. Somatic generation of antibody diversity. Nature 302, 575–581 (1983).

2. Muramatsu, M. et al. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102, 553–563 (2000).

3. Muramatsu, M. et al. Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J. Biol. Chem. 274, 18470–18476 (1999).

4. Martin, A. & Scharff, M. D. AID and mismatch repair in antibody diversification. Nat. Rev. Immunol. 2, 605–614 (2002).

5. Chaudhuri, J. & Alt, F. W. Class-switch recombination: interplay of transcription, DNA deamination and DNA repair. Nat. Rev. Immunol. 4, 541–552 (2004).

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