Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/nature17437.pdf
Reference45 articles.
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3. Melton, C., Reuter, J. A., Spacek, D. V. & Snyder, M. Recurrent somatic mutations in regulatory regions of human cancer genomes. Nature Genet. 47, 710–716 (2015)
4. Poulos, R. C. et al. Systematic screening of promoter regions pinpoints functional cis-regulatory mutations in a cutaneous melanoma genome. Mol. Cancer Res. 13, 1218–1226 (2015)
5. Hu, J., Adar, S., Selby, C. P., Lieb, J. D. & Sancar, A. Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution. Genes Dev. 29, 948–960 (2015)
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