Immune response and survival of refractory cancer patients who received TGF-β2 antisense/GM-CSF gene modified autologous tumor cell (TAG) vaccine-Reference-Cited by-同舟云学术

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Immune response and survival of refractory cancer patients who received TGF-β2 antisense/GM-CSF gene modified autologous tumor cell (TAG) vaccine

Published:2013-03-07 Issue:9 Volume:20 Page:875-879
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Nemunaitis J,Senzer N,Olivares J,Kumar P,Barve M,Kuhn J,Nemunaitis T,Magee M,Yu Y,Wallraven G,Pappen B O,Maples P B

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/gt20139.pdf

Reference17 articles.

1. Nemunaitis J, Sterman D, Jablons D, Smith JW, Fox B, Maples P et al. Granulocyte-macrophage colony-stimulating factor gene-modified autologous tumor vaccines in non-small-cell lung cancer. J Natl Cancer Inst 2004; 96: 326–331.

2. Nemunaitis J, Dillman RO, Schwarzenberger PO, Senzer N, Cunningham C, Cutler J et al. Phase II study of belagenpumatucel-L, a transforming growth factor beta-2 antisense gene-modified allogeneic tumor cell vaccine in non-small-cell lung cancer. J Clin Oncol 2006; 24: 4721–4730.

3. Olivares J, Kumar P, Yu Y, Maples PB, Senzer N, Bedell C et al. Phase I trial of TGF-{beta}2 antisense GM-CSF gene-modified autologous tumor cell (TAG) vaccine. Clin Cancer Res 2011; 17: 183–192.

4. Nemunaitis JJ . Are vaccines making a comeback in non-small-cell lung cancer? J Clin Oncol 2008; 26: 1402–1403.

5. Wheler J, Tsimberidou AM, Hong D, Naing A, Jackson T, Liu S et al. Survival of patients in a Phase 1 Clinic: the M D Anderson Cancer Center experience. Cancer 2009; 115: 1091–1099.

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