Towards the sustainable discovery and development of new antibiotics

Author:

Miethke Marcus,Pieroni Marco,Weber TilmannORCID,Brönstrup Mark,Hammann Peter,Halby Ludovic,Arimondo Paola B.,Glaser Philippe,Aigle BertrandORCID,Bode Helge B.ORCID,Moreira Rui,Li Yanyan,Luzhetskyy Andriy,Medema Marnix H.ORCID,Pernodet Jean-LucORCID,Stadler Marc,Tormo José Rubén,Genilloud Olga,Truman Andrew W.ORCID,Weissman Kira J.ORCID,Takano ErikoORCID,Sabatini StefanoORCID,Stegmann Evi,Brötz-Oesterhelt Heike,Wohlleben Wolfgang,Seemann MyriamORCID,Empting Martin,Hirsch Anna K. H.,Loretz Brigitta,Lehr Claus-Michael,Titz AlexanderORCID,Herrmann Jennifer,Jaeger Timo,Alt Silke,Hesterkamp Thomas,Winterhalter MathiasORCID,Schiefer AndreaORCID,Pfarr KennethORCID,Hoerauf Achim,Graz Heather,Graz MichaelORCID,Lindvall Mika,Ramurthy Savithri,Karlén Anders,van Dongen Maarten,Petkovic Hrvoje,Keller AndreasORCID,Peyrane Frédéric,Donadio Stefano,Fraisse Laurent,Piddock Laura J. V.ORCID,Gilbert Ian H.ORCID,Moser Heinz E.ORCID,Müller RolfORCID

Publisher

Springer Science and Business Media LLC

Subject

General Chemical Engineering,General Chemistry

Reference354 articles.

1. Ventola, C. L. The antibiotic resistance crisis: part 1: causes and threats. Pharm. Ther. 40, 277–283 (2015). A comprehensive summary of the emergence of antibiotic resistance and the associated clinical and economic burden.

2. Byrne, M. K. et al. The drivers of antibiotic use and misuse: the development and investigation of a theory driven community measure. BMC Public. Health 19, 1425 (2019).

3. Nadimpalli, M. L. et al. Urban informal settlements as hotspots of antimicrobial resistance and the need to curb environmental transmission. Nat. Microbiol. 5, 787–795 (2020).

4. World Health Organization (WHO). WHO report on surveillance of antibiotic consumption 2016–2018 early implementation (WHO, 2018) https://www.who.int/medicines/areas/rational_use/oms-amr-amc-report-2016-2018/en/

5. Schrader, S. M., Vaubourgeix, J. & Nathan, C. Biology of antimicrobial resistance and approaches to combat it. Sci. Trans. Med. 12, eaaz6992 (2020).

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