Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer’s disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep29760.pdf
Reference47 articles.
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2. Moreth, J., Mavoungou, C. & Schindowski, K. Passive anti-amyloid immunotherapy in Alzheimer’s disease: What are the most promising targets? Immun. Ageing 10, 18 (2013).
3. Iwata, N., Higuchi, M. & Saido, T. C. Metabolism of amyloid-b peptide and Alzheimer’s disease. Pharmacol. Therapeut. 108, 129–148 (2005).
4. Wang, D. S., Iwata, N., Hama, E., Saido, T. C. & Dickson, D. W. Oxidized neprilysin in aging and Alzheimer’s disease brains. Biochem. Biophys. Res. Commun. 310, 236–241 (2003).
5. Hellstrom-Lindahl, E., Ravid, R. & Nordberg, A. Age-dependent decline of neprilysin in Alzheimer’s disease and normal brain: inverse correlation with A beta levels. Neurobiol. Aging 29, 210–221 (2008).
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