Non-canonical FLT3 alterations reveal novel germline FLT3 variants leading to somatic gene rescue mutations
Author:
Funder
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41408-024-01104-9.pdf
Reference15 articles.
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3. Bacher U, Haferlach C, Kern W, Haferlach T, Schnittger S. Prognostic relevance of FLT3-TKD mutations in AML: the combination matters—an analysis of 3082 patients. Blood. 2008;111:2527–37.
4. Clark JJ, Cools J, Curley DP, Yu J-C, Lokker NA, Giese NA, et al. Variable sensitivity of FLT3 activation loop mutations to the small molecule tyrosine kinase inhibitor MLN518. Blood. 2004;104:2867–72.
5. Ge S-S, Qiu Q-C, Dai H-P, Shen X-D, Wu T-M, Du J-H, et al. Mutation spectrum of FLT3 and significance of non-canonical FLT3 mutations in haematological malignancy. Br J Haematol. 2023;202:539–49.
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