Supersensitivity to allosteric GABAA receptor modulators and alcohol in mice lacking PKCε

Author:

Hodge Clyde W.,Mehmert Kristin K.,Kelley Stephen P.,McMahon Thomas,Haywood Ashley,Olive M. Foster,Wang Dan,Sanchez-Perez Ana Maria,Messing Robert O.

Publisher

Springer Science and Business Media LLC

Subject

General Neuroscience

Reference46 articles.

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2. Hodge, C. W. & Cox, A. A. The discriminative stimulus effects of ethanol are mediated by NMDA and GABA(A) receptors in specific limbic brain regions. Psychopharmacology 139, 95–107 (1998).

3. Dietrich, R., Dunwiddie, T., Harris, R. & Erwin, V. Mechanism of action of ethanol: initial central nervous system actions. Pharmacol. Rev. 41, 489–537 (1989).

4. Allan, A. & Harris, R. Acute and chronic ethanol treatments alter GABA receptor-operated chloride channels. Pharmacol. Biochem. Behav. 27, 665–670 (1987).

5. Mehta, A. K. & Ticku, M. K. Ethanol potentiation of GABAergic transmission in cultured spinal cord neurons involves γ-aminobutyric acidA-gated chloride channels. J. Pharmacol. Exp. Ther. 246, 558–564 (1988).

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