Adipocytes reprogram cancer cell metabolism by diverting glucose towards glycerol-3-phosphate thereby promoting metastasis-Reference-Cited by-同舟云学术

Adipocytes reprogram cancer cell metabolism by diverting glucose towards glycerol-3-phosphate thereby promoting metastasis

Published:2023-08-31 Issue:9 Volume:5 Page:1563-1577
ISSN:2522-5812
Container-title:Nature Metabolism
language:en
Short-container-title:Nat Metab

Author:

Mukherjee Abir^ORCID,Bezwada Divya^ORCID,Greco Francesco^ORCID,Zandbergen Malu,Shen Tong,Chiang Chun-Yi^ORCID,Tasdemir Medine^ORCID,Fahrmann Johannes,Grapov Dmitry^ORCID,La Frano Michael R.^ORCID,Vu Hieu S.,Faubert Brandon^ORCID,Newman John W.^ORCID,McDonnell Liam A.^ORCID,Nezi Luigi^ORCID,Fiehn Oliver^ORCID,DeBerardinis Ralph J.^ORCID,Lengyel Ernst^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Ovarian Cancer Research Fund

United States Department of Defense | United States Army | Army Medical Command | Congressionally Directed Medical Research Programs

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Physiology (medical),Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

https://www.nature.com/articles/s42255-023-00879-8.pdf

Reference56 articles.

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2. Mukherjee, A., Bilecz, A. J. & Lengyel, E. The adipocyte microenvironment and cancer. Cancer Metastasis Rev. https://doi.org/10.1007/s10555-022-10059-x (2022).

3. Eckert, M. A. et al. Genomics of ovarian cancer progression reveals diverse metastatic trajectories including intraepithelial metastasis to the fallopian tube. Cancer Discov. 6, 1342–1351 (2016).

4. Nieman, K. M. et al. Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat. Med. 17, 1498–1503 (2011).

5. Mukherjee, A. et al. Adipocyte-induced FABP4 expression in ovarian cancer cells promotes metastasis and mediates carboplatin resistance. Cancer Res. 80, 1748–1761 (2020).

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