Small intestinal CaSR-dependent and CaSR-independent protein sensing regulates feeding and glucose tolerance in rats
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Physiology (medical),Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
https://www.nature.com/articles/s42255-023-00942-4.pdf
Reference69 articles.
1. Modvig, I. M., Kuhre, R. E. & Holst, J. J. Peptone-mediated glucagon-like peptide-1 secretion depends on intestinal absorption and activation of basolaterally located calcium-sensing receptors. Physiol. Rep. 7, e14056 (2019).
2. Mace, O. J., Schindler, M. & Patel, S. The regulation of K- and L-cell activity by GLUT2 and the calcium-sensing receptor CasR in rat small intestine. J. Physiol. 590, 2917–2936 (2012).
3. Acar, I., Cetinkaya, A., Lay, I. & Ileri-Gurel, E. The role of calcium sensing receptors in GLP-1 and PYY secretion after acute intraduodenal administration of L-tryptophan in rats. Nutr. Neurosci. 23, 481–489 (2020).
4. Diakogiannaki, E. et al. Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor. Diabetologia 56, 2688–2696 (2013).
5. Modvig, I. M. et al. Amino acids differ in their capacity to stimulate GLP-1 release from the perfused rat small intestine and stimulate secretion by different sensing mechanisms. Am. J. Physiol. Endocrinol. Metab. 320, E874–E885 (2021).
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