High-throughput and combinatorial gene expression on a chip for metabolism-induced toxicology screening-Reference-Cited by-同舟云学术

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High-throughput and combinatorial gene expression on a chip for metabolism-induced toxicology screening

Published:2014-05-06 Issue:1 Volume:5 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Kwon Seok Joon,Lee Dong Woo,Shah Dhiral A.,Ku Bosung,Jeon Sang Youl,Solanki Kusum,Ryan Jessica D.,Clark Douglas S.,Dordick Jonathan S.,Lee Moo-Yeal

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms4739.pdf

Reference45 articles.

1. Lee, M. Y. & Dordick, J. S. High-throughput human metabolism and toxicity analysis. Curr. Opin. Biotechnol. 17, 619–627 (2006).

2. Guengerich, F. P. Cytochrome P450s and other enzymes in drug metabolism and toxicity. AAPS J. 8, E101–E111 (2006).

3. Nebert, D. W. & Bingham, E. Pharmacogenomics: out of the lab and into the community. Trends Biotechnol. 19, 519–523 (2001).

4. Park, B. K. et al. Managing the challenge of chemically reactive metabolites in drug development. Nat. Rev. Drug Discov. 10, 292–306 (2011).

5. Brandon, E. F., Raap, C. D., Meijerman, I., Beijnen, J. H. & Schellens, J. H. An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons. Toxicol. Appl. Pharmacol. 189, 233–246 (2003).

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