Imatinib and the long tail of targeted drug development

Author:

Carlisle Benjamin G.ORCID,Zheng Tiger,Kimmelman JonathanORCID

Publisher

Springer Science and Business Media LLC

Subject

Oncology

Reference8 articles.

1. TIME. Drugs that fight cancer. TIME http://content.time.com/time/covers/0,16641,20010528,00.html (2001).

2. Cohen, M. H. et al. Approval summary for imatinib mesylate capsules in the treatment of chronic myelogenous leukemia. Clin. Cancer Res. 8, 935–942 (2002).

3. FDA. Drugs@FDA: FDA approved drug products. FDA https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=021588 (2018).

4. Yam, C. et al. A phase II study of imatinib mesylate and letrozole in patients with hormone receptor-positive metastatic breast cancer expressing c-kit or PDGFR-β. Invest. New Drugs 36, 1103–1109 (2018).

5. Carlisle, B. G. et al. Patient benefit and risk in anticancer drug development: a systematic review of the ixabepilone trial portfolio. medRxiv https://www.medrxiv.org/content/10.1101/19003467v1 (2019).

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