Therapeutic strategies to target RAS-mutant cancers
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology
Link
http://www.nature.com/articles/s41571-018-0105-0.pdf
Reference178 articles.
1. Simanshu, D. K., Nissley, D. V. & McCormick, F. RAS proteins and their regulators in human disease. Cell 170, 17–33 (2017).
2. Vetter, I. R. & Wittinghofer, A. The guanine nucleotide-binding switch in three dimensions. Science 294, 1299–1304 (2001).
3. Nussinov, R., Tsai, C.-J. & Jang, H. Oncogenic Ras isoforms signaling specificity at the membrane. Cancer Res. 78, 593–602 (2018).
4. Keeton, A. B., Salter, E. A. & Piazza, G. A. The RAS-effector interaction as a drug target. Cancer Res. 77, 221–226 (2017).
5. Ryan, M. B., Der, C. J., Wang-Gillam, A. & Cox, A. D. Targeting RAS-mutant cancers: is ERK the key? Trends Cancer 1, 183–198 (2015).
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