Surgically treated pneumonic-type lung adenocarcinoma with long survival characteristics

Abstract

Aims: Pneumonic-type lung adenocarcinoma is defined as a pneumonia-like area of infiltration or consolidation involving a region of the lung. These carcinomas, which are suitable for curative treatment options and have a long survival when detected at an early stage, may resemble infectious or inflammatory lung diseases due to their radiological appearance and clinical findings, may lead to potential delays or difficulties in diagnosis, and this may cause progression in patients who are suitable for curative treatment options. Methods: A total of 41 patients which were surgically treated between 2011-2020 and diagnosed pathologically with pneumonic-type adenocarcinoma. The patents’ TTF-1, type of operation, pathological stages, overall/progression-free survival, as well as overall/progression-free survival according to the type of operation and radiological appearance, were also evaluated. Results: The study included 41 patients. Although overall survival times were long, there was no statistically significant defference between wedge resection and lobectomy group in overall survival by operation type. Although progression-free survival times were long, there was no statistically significant defference between wedge resection and lobectomy group in progression-free survival by operation type. There was no statistically significant difference between solid and consolidated groups in terms of overall survival and progression-free survival according to radiological appearances. There was no statistically significant difference between TTF-1 positive and negative groups in overall survival. Conclusion: Pneumonic-type lung adenocarcinomas respond to curative treatments when diagnosed at an early stage. The optimal treatment method for operable patients is surgery, which is associated with prolonged survival.