The ionization of a buried glutamic acid is thermodynamically linked to the stability of Leishmania mexicana triose phosphate isomerase
Author:
Publisher
Wiley
Subject
Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1046/j.1432-1327.2000.01254.x/fullpdf
Reference44 articles.
1. Nanometric design of extraordinary hydrophobic-induced pKa shifts for aspartic acid: relevance to protein mechanisms;Urry;Biopolymers,1994
2. In a staphylococcal nuclease mutant the side-chain of a lysine replacing valine 66 is fully buried in the hydrophobic core;Stites;J. Mol. Biol.,1991
3. The conserved, buried aspartic acid in oxidized Escherichia coli thioredoxin has a pKa of 7.5. Its titration produces a related shift in global stability;Langsetmo;Biochemistry,1991
4. Linkage of thioredoxin stability to titration of ionizable group with perturbed pKa;Langsetmo;Biochemistry,1991
5. Ionizable P1 residues in serine proteinase inhibitors undergo large pK shifts on complex formation;Qasim;J. Biol. Chem.,1995
Cited by 47 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Experimental structure based drug design (SBDD) applications for anti‐leishmanial drugs: A paradigm shift?;Medicinal Research Reviews;2023-12-24
2. The Role of Asn11 in Catalysis by Triosephosphate Isomerase;Biochemistry;2023-05-10
3. Analysis of Biologics Molecular Descriptors towards Predictive Modelling for Protein Drug Development Using Time-Gated Raman Spectroscopy;Pharmaceutics;2022-08-05
4. Parallel molecular mechanisms for enzyme temperature adaptation;Science;2021-03-05
5. Perdeuteration, large crystal growth and neutron data collection ofLeishmania mexicanatriose-phosphate isomerase E65Q variant;Acta Crystallographica Section F Structural Biology Communications;2019-04-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3