Personalized Injury Reduction Strategies in Sports Medicine: Lessons Learned from Advances in Breast Cancer Treatment: A Clinical Commentary

Author:

Bullock Garrett112,Collins Gary23,Adams Rober4,Thigpen Charles5,Shanley Ellen5

Affiliation:

1. Wake Forest School of Medicine

2. University of Oxford

3. Oxford University Hospitals NHS Foundation Trust

4. University of North Carolina School of Medicine

5. ATI Physical Therapy

Abstract

Background Injury rates across sport have risen over the past twenty years, despite increased efforts in training and injury prevention. The rise in injury rates suggest that current approaches to estimating injury risk and risk management are not effective. One factor limiting progress is the inconsistency in screening, risk assessment, and risk management strategies to guide injury mitigation approaches. Clinical Question How can sports physical therapists identify and apply lessons learned from other healthcare fields to improve athlete injury risk and risk management strategies? Key Results Breast cancer mortality has consistently decreased over the last 30 years, largely attributed to advances in personalizing the prevention and treatment strategies which include modifiable and non-modifiable factors when assessing risk, the transition to personalized medicine, and the systematic approach used to investigate individual risk factors. Three critical phases have facilitated the identification and importance of individual risk factors and developing targeted, personalized strategies for breast cancer risk including: 1) Establishing the potential relationship between factors and outcomes; 2) Prospectively investigate the strength and direction of the relationship; 3) Investigating if intervening on identified factors alters prognosis. Clinical Application Applying lessons learned from other healthcare fields could improve shared decision making between the clinician and athlete concerning risk assessment and management. Examples include calculating only non-modifiable risk, creating individualized screening schedules based on risk assessment, or calculating the influence of each intervention on the athlete’s injury risk. A systematic approach to identify and intervene on risk is needed to improve athlete outcomes.

Publisher

International Journal of Sports Physical Therapy

Subject

Rehabilitation,Orthopedics and Sports Medicine,Physical Therapy, Sports Therapy and Rehabilitation

Reference63 articles.

1. Breast cancer risk from modifiable and nonmodifiable risk factors among white women in the United States;Paige Maas;JAMA Oncology,2016

2. Proportion of invasive breast cancer attributable to risk factors modifiable after menopause;B. L. Sprague;American Journal of Epidemiology,2008

3. Advances in breast cancer: pathways to personalized medicine;Olufunmilayo I. Olopade;Clinical Cancer Research,2008

4. Polygenic risk scores for prediction of breast cancer and breast cancer subtypes;Nasim Mavaddat;The American Journal of Human Genetics,2019

5. Methodological challenges in the evaluation of prognostic factors in breast cancer;D.G. Altman;Breast Cancer Res Treat

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