A Physiologically Based Pharmacokinetic Model to Predict Disposition of CYP2D6 and CYP1A2 Metabolized Drugs in Pregnant Women-Reference-Cited by-同舟云学术

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A Physiologically Based Pharmacokinetic Model to Predict Disposition of CYP2D6 and CYP1A2 Metabolized Drugs in Pregnant Women

Published:2013-01-25 Issue:4 Volume:41 Page:801-813
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Ke Alice Ban,Nallani Srikanth C.,Zhao Ping,Rostami-Hodjegan Amin,Isoherranen Nina,Unadkat Jashvant D.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference67 articles.

1. The antitussive effect of dextromethorphan in relation to CYP2D6 activity

2. Assessment of Activity Levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 Genes by Population Pharmacokinetics of Dextromethorphan

3. Anatomical, Physiological and Metabolic Changes with Gestational Age during Normal Pregnancy

4. Safety, Tolerability, and Pharmacokinetics of the N -Methyl- d -Aspartate Antagonist Dextrorphan in Patients With Acute Stroke

5. Pharmacokinetic and pharmacodynamic studies of oral clonidine in normotensive subjects

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1. Physiologically based pharmacokinetic (PBPK) modeling of the role of CYP2D6 polymorphism for metabolic phenotyping with dextromethorphan;Frontiers in Pharmacology;2022-10-24

2. Antidepressants and Antipsychotics in Human Pregnancy: Transfer Across the Placenta and Opportunities for Modeling Studies;The Journal of Clinical Pharmacology;2022-09

3. Predicting Human Fetal Drug Exposure Through Maternal‐Fetal PBPK Modeling and In Vitro or Ex Vivo Studies;The Journal of Clinical Pharmacology;2022-09

4. Physiologically based pharmacokinetic (PBPK) modeling of the role of CYP2D6 polymorphism for metabolic phenotyping with dextromethorphan;2022-08-25

5. Physiologically Based Pharmacokinetic Modeling to Describe the CYP2D6 Activity Score-Dependent Metabolism of Paroxetine, Atomoxetine and Risperidone;Pharmaceutics;2022-08-18

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