N-Terminal Modification of the Tetrapeptide Arg-Leu-Tyr-Glu, a Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) Antagonist, Improves Antitumor Activity by Increasing its Stability against Serum Peptidases
Author:
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Subject
Pharmacology,Molecular Medicine
Reference50 articles.
1. Direct endothelial junction restoration results in significant tumor vascular normalization and metastasis inhibition in mice
2. Ramucirumab: preclinical research and clinical development;Aprile;OncoTargets Ther,2014
3. Arg-Leu-Tyr-Glu tetrapeptide inhibits tumor progression by suppressing angiogenesis and vascular permeability via VEGF receptor-2 antagonism;Baek;Oncotarget,2017
4. The tetrapeptide Arg-Leu-Tyr-Glu inhibits VEGF-induced angiogenesis;Baek;Biochem Biophys Res Commun,2015
5. Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
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