Difluoromethyl Bioisostere: Examining the “Lipophilic Hydrogen Bond Donor” Concept
Author:
Affiliation:
1. The Department of Organic Chemistry, Israel Institute for Biological Research, Ness-Ziona 74100, Israel
Funder
Prime Minister’s Office, Israel
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01691
Reference42 articles.
1. Applications of Fluorine in Medicinal Chemistry
2. Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
3. Fluorine in Pharmaceuticals: Looking Beyond Intuition
4. Fluorine in Medicinal Chemistry
5. A Fluorine Scan at the Catalytic Center of Thrombin: CF, COH, and COMe Bioisosterism and Fluorine Effects on pKa and logD Values
Cited by 433 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Cu-catalyzed three-component aminodifluoroalkylative cyclization of styrenes: Access to α,α-difluoro-γ-lactams;Molecular Catalysis;2024-03
2. Difluorocarbene-enabled synthesis of 18F-radiotracers in positron emission tomography;Journal of Fluorine Chemistry;2024-02
3. Difluoromethylated Difunctionalization of Alkenes under Visible Light;The Journal of Organic Chemistry;2024-02-01
4. Diluent modified weakly solvating electrolyte for fast-charging high-voltage lithium metal batteries;Chinese Chemical Letters;2024-02
5. Difluoroethylation Reactions of Organic Compounds;European Journal of Organic Chemistry;2024-01-22
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3