Exploring Translocator Protein (TSPO) Medicinal Chemistry: An Approach for Targeting Radionuclides and Boron Atoms to Mitochondria-Reference-Cited by-同舟云学术

Exploring Translocator Protein (TSPO) Medicinal Chemistry: An Approach for Targeting Radionuclides and Boron Atoms to Mitochondria

Published:2021-07-13 Issue:14 Volume:64 Page:9649-9676
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Giordani Antonio¹,Menziani Maria Cristina²^ORCID,Moresco Rosa Maria³,Matarrese Mario³,Paolino Marco⁴^ORCID,Saletti Mario⁴^ORCID,Giuliani Germano⁴,Anzini Maurizio⁴^ORCID,Cappelli Andrea⁴^ORCID

Affiliation:

1. Rottapharm Biotech S.p.A., Via Valosa di Sopra 9, 20900 Monza, Italy

2. Dipartimento di Scienze Chimiche e Geologiche, Università di Modena e Reggio Emilia, Via Campi 103, 41121 Modena, Italy

3. Department of Medicine and Surgery, University of Milan-Bicocca, Nuclear Medicine Department, San Raffaele Scientific Institute, IBFM-CNR, Via Olgettina 60, 20132 Milano, Italy

4. Dipartimento di Biotecnologie, Chimica e Farmacia (Dipartimento di Eccellenza 2018−2022), Università di Siena, Via A. Moro 2, 53100 Siena, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00379

Reference193 articles.

1. Translocator Protein 18 kDa (TSPO): An Old Protein with New Functions?

2. Insight into the Structural Features of TSPO: Implications for Drug Development

3. An update into the medicinal chemistry of translocator protein (TSPO) ligands

4. Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding.

5. Subtype Selective γ-Aminobutyric Acid Type A Receptor (GABAAR) Modulators Acting at the Benzodiazepine Binding Site: An Update

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