Discovery of Orally Available Retinoic Acid Receptor-Related Orphan Receptor γ-t/Dihydroorotate Dehydrogenase Dual Inhibitors for the Treatment of Refractory Inflammatory Bowel Disease-Reference-Cited by-同舟云学术

Discovery of Orally Available Retinoic Acid Receptor-Related Orphan Receptor γ-t/Dihydroorotate Dehydrogenase Dual Inhibitors for the Treatment of Refractory Inflammatory Bowel Disease

Published:2021-12-27 Issue:1 Volume:65 Page:592-615
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chen Ji-An¹,Ma Hui²,Liu Zehui²,Tian Jinlong¹,Lu Sisi²,Fang Wenqing²,Ze Shuyin³,Lu Weiqiang³^ORCID,Xie Qiong¹⁴,Huang Jin²,Wang Yonghui¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, China

2. Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China

3. Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China

4. Fudan Zhangjiang Institute, 666 Zhangheng Road, Shanghai 201203, China

Funder

Natural Science Foundation of Shanghai

Ministry of Science and Technology of the People's Republic of China

Shanghai Municipal Education Commission

National Natural Science Foundation of China

Shanghai Biopharmaceutical and Technology Supporting Plan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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