Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras
Author:
Affiliation:
1. Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093−0358, United States
Funder
UC San Diego Foundation
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00482
Reference70 articles.
1. Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation
2. Small-Molecule Approaches to Targeted Protein Degradation
3. Diazaborines as New Inhibitors of Human Neutrophil Elastase
4. Drugging the 'undruggable' cancer targets
5. Targeting the Undruggable Proteome: The Small Molecules of My Dreams
Cited by 79 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Insight into Recent Advances in Degrading Androgen Receptor for Castration-Resistant Prostate Cancer;Cancers;2024-02-04
2. What influences the activity of Degrader−Antibody conjugates (DACs);European Journal of Medicinal Chemistry;2024-02
3. Journey of Von Hippel-Lindau (VHL) E3 ligase in PROTACs design: From VHL ligands to VHL-based degraders;European Journal of Medicinal Chemistry;2024-02
4. Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor;Cell Chemical Biology;2024-02
5. BacPROTACs targeting Clp protease: a promising strategy for anti-mycobacterial drug discovery;Frontiers in Chemistry;2024-01-31
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3