A Medicinal Chemistry Perspective on FDA-Approved Small Molecule Drugs with a Covalent Mechanism of Action
Author:
Affiliation:
1. Department of Discovery Chemistry, MSD, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, United Kingdom
2. Department of Discovery Chemistry, Merck & Co., Inc., 33 Ave. Louis Pasteur, Boston, Massachusetts 02215, United States
Publisher
American Chemical Society (ACS)
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c02661
Reference51 articles.
1. Advances in covalent drug discovery
2. The Ascension of Targeted Covalent Inhibitors
3. 10 Years Into the Resurgence of Covalent Drugs
4. Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries
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