Discovery of Novel Azaindoles as Potent and Selective PI3Kδ Inhibitors for Treatment of Multiple Sclerosis-Reference-Cited by-同舟云学术

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Discovery of Novel Azaindoles as Potent and Selective PI3Kδ Inhibitors for Treatment of Multiple Sclerosis

Published:2024-05-16 Issue:11 Volume:67 Page:9628-9644
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yu Mengyao¹,Wang Xian¹,Tang Yongmei¹,Wang Longling¹,Hu Xueping²,Weng Qinjie¹³,Wang Jiajia¹,Cui Sunliang¹^ORCID

Affiliation:

1. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China

2. Institute of Frontier Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Qingdao 266237, China

3. Taizhou Institute of Zhejiang University, Taizhou 318000, China

Funder

National Program for Support of Top-notch Young Professionals

Key Research and Development Program of Zhejiang Province

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Zhejiang Provincial Outstanding Youth Science Foundation

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00788

Reference36 articles.

1. Multiple sclerosis

2. Multiple sclerosis

3. Multiple sclerosis: Neuroimmune crosstalk and therapeutic targeting

4. Multiple sclerosis: immunopathogenesis and controversies in defining the cause

5. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria

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