Structure–Activity Relationship Studies of Aryl Sulfoxides as Reversible Monoacylglycerol Lipase Inhibitors-Reference-Cited by-同舟云学术

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Structure–Activity Relationship Studies of Aryl Sulfoxides as Reversible Monoacylglycerol Lipase Inhibitors

Published:2024-07-11 Issue:14 Volume:67 Page:12331-12348
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Jiang Ming¹,Huizenga Mirjam C. W.¹^ORCID,Mohr Florian¹,Amedi Avand¹,Bakker Renze¹,van den Berg Richard J. B. H. N.²,Deng Hui¹,van der Wel Tom¹,van Boeckel Constant A.A.¹,van der Stelt Mario¹^ORCID

Affiliation:

1. Department of Molecular Physiology, Leiden University and Oncode Institute, Leiden 2333 CC, Netherlands

2. Department of Bio-organic Synthesis, Leiden University, Leiden 2333 CC, Netherlands

Funder

Karlsruhe House of Young Scientists

Karlsruhe Institute of Technology

Oncode Institute

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

OncoDrugs

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01037

Reference28 articles.

1. Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation

2. Monoacylglycerol lipase - a target for drug development?

3. Monoacylglycerol lipase inhibitors: modulators for lipid metabolism in cancer malignancy, neurological and metabolic disorders

4. A Comprehensive Profile of Brain Enzymes that Hydrolyze the Endocannabinoid 2-Arachidonoylglycerol

5. Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders

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