Discovery of Novel, Selective, and Nonbasic Agonists for the Kappa-Opioid Receptor Determined by Salvinorin A-Based Virtual Screening-Reference-Cited by-同舟云学术

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Discovery of Novel, Selective, and Nonbasic Agonists for the Kappa-Opioid Receptor Determined by Salvinorin A-Based Virtual Screening

Published:2024-08-01 Issue:16 Volume:67 Page:13788-13801
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Puls Kristina¹,Olivé-Marti Aina-Leonor²,Hongnak Siriwat²^ORCID,Lamp David²,Spetea Mariana²^ORCID,Wolber Gerhard¹^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2-4, 14195 Berlin, Germany

2. Department of Pharmaceutical Chemistry, Institute of Pharmacy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria

Funder

Universität Innsbruck

Austrian Science Fund

Deutsche Forschungsgemeinschaft

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00590

Reference121 articles.

1. Opioid Analgesia and Opioid-Induced Adverse Effects: A Review

2. A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists

3. Opioid mechanisms and opioid drugs

4. The United States opioid epidemic

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