Synthesis of Bleomycin-Inspired RNA Ligands Targeting the Biogenesis of Oncogenic miRNAs-Reference-Cited by-同舟云学术

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Synthesis of Bleomycin-Inspired RNA Ligands Targeting the Biogenesis of Oncogenic miRNAs

Published:2023-07-14 Issue:15 Volume:66 Page:10639-10657
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Maucort Chloé¹,Bonnet Maurinne¹,Ortuno Jean-Claude²,Tucker Gordon²,Quissac Emie³,Verreault Maïté³,Azoulay Stéphane¹,Di Giorgio Christophe¹^ORCID,Di Giorgio Audrey¹,Duca Maria¹^ORCID

Affiliation:

1. CNRS, Institute of Chemistry of Nice (ICN), Université Côte d’Azur, 28 avenue Valrose, 06100 Nice, France

2. Institut de Recherche Servier, 125 chemin de Ronde, 78290 Croissy-sur-Seine, France

3. Institut du Cerveau-Paris Brain Institute-ICM, Inserm, CNRS, APHP, Hôpital de la Pitié Salpêtrière, Sorbonne Université, F-75013 Paris, France

Funder

Agence Nationale de la Recherche

Fondation ARC pour la Recherche sur le Cancer

Minist?re de l'Education Nationale, de l'Enseignement Superieur et de la Recherche

Institut de Recherche Servier

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00797

Reference39 articles.

1. Targeting RNA structures with small molecules

2. Principles for targeting RNA with drug-like small molecules

3. Targeting RNA with small molecules: from fundamental principles towards the clinic

4. Ribosome-targeting antibiotics and mechanisms of bacterial resistance

5. Risdiplam, the First Approved Small Molecule Splicing Modifier Drug as a Blueprint for Future Transformative Medicines

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