Structure–Activity Relationship and Biological Investigation of a REV-ERBα-Selective Agonist SR-29065 (<b>34</b>) for Autoimmune Disorders-Reference-Cited by-同舟云学术

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Structure–Activity Relationship and Biological Investigation of a REV-ERBα-Selective Agonist SR-29065 (34) for Autoimmune Disorders

Published:2023-10-27 Issue:21 Volume:66 Page:14815-14823
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

He Yuanjun¹,Zhu Di¹,Greenman Kevin²,Ruiz Claudia¹,Shang Jinsai¹^ORCID,Lu Qun¹,Kojetin Douglas J.¹^ORCID,Drakas Robert³,Cameron Michael D.¹^ORCID,Lizarzaburu Mike²,Solt Laura A.¹,Kamenecka Theodore M.¹

Affiliation:

1. The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, Florida 33458, United States

2. ChemPartner Corporation, 280 Utah Avenue, Suite 100, South San Francisco, California 94080, United States

3. ShangPharma Innovation, 280 Utah Avenue, Suite 100, South San Francisco, California 94080, United States

Funder

National Cancer Institute

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01413

Reference22 articles.

1. A new orphan member of the nuclear hormone receptor superfamily closely related to Rev-Erb.

2. Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors.

3. Orphan nuclear receptors: therapeutic opportunities in skeletal muscle

4. Th17 Cell Differentiation: The Long and Winding Road

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