Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition-Reference-Cited by-同舟云学术

Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition

Published:2023-10-11 Issue:20 Volume:66 Page:14278-14302
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kücükdisli Murat¹,Bel-Abed Hassen¹,Cirillo Davide¹^ORCID,Lo Wen-Ting¹,Efrém Nina-Louisa¹,Horatscheck André¹,Perepelittchenko Liudmila¹,Prokofeva Polina²,Ehret Theresa A. L.³⁴,Radetzki Silke¹,Neuenschwander Martin¹,Specker Edgar¹^ORCID,Médard Guillaume²^ORCID,Müller Susanne³⁴^ORCID,Wilhelm Stephanie²^ORCID,Kuster Bernhard²^ORCID,von Kries Jens Peter¹,Haucke Volker¹,Nazaré Marc¹^ORCID

Affiliation:

1. Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Campus Berlin-Buch, 13125 Berlin, Germany

2. Chair of Proteomics and Bioanalytics, Technical University of Munich, 85354 Freising, Germany

3. Institute of Pharmaceutical Chemistry, Johann Wolfgang Goethe University, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany

4. Buchmann Institute for Molecular Life Sciences and Structural Genomics Consortium (SGC), Max-von-Laue-Str. 15, 60438 Frankfurt am Main, Germany

Funder

Deutsche Forschungsgemeinschaft

H2020 Marie Sklodowska-Curie Actions

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01319

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4. The emerging mechanisms of isoform-specific PI3K signalling

5. Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate