Liquiritigenin Confers Liver Protection by Enhancing NRF2 Signaling through Both Canonical and Non-canonical Signaling Pathways

Author:

Shi Mengjiao123,Zhang Jian14,Li Miaomiao15,Zhao Yaping123,Guo Ying13,Xu Jiayi123,Liu Rongrong123,Li Zongfang13,Ren Dongmei6ORCID,Liu Pengfei1237ORCID

Affiliation:

1. National & Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, China

2. International Joint Research Center on Cell Stress and Disease Diagnosis and Therapy, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, China

3. Shaanxi Provincial Clinical Research Center for Hepatic & Splenic Diseases, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, China

4. Department of General Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, China

5. Department of Regenerative Medicine, School of Pharmaceutical Science, Jilin University, Changchun 130021, China

6. Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China

7. Key Laboratory of Environment and Genes Related To Diseases, Xi’an Jiaotong University, Ministry of Education of China, Xi’an 710061, China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shaanxi Province

Key Research and Development Projects of Shaanxi Province

Innovation Capability Support Program of Shaanxi Province

Xi'an Jiaotong University

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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