Discovery of 4-Ethoxy-6-chloro-5-azaindazoles as Novel PDE4 Inhibitors for the Treatment of Alcohol Use Disorder and Alcoholic Liver Diseases

Author:

Zheng Lei1ORCID,Aimaiti Zulihuma1,Long Lu1,Xia Chuang1,Wang Wenya1,Zhou Zhong-Zhen1ORCID

Affiliation:

1. Innovation Program of Drug Research on Neurological and Metabolic Diseases, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China

Funder

Guangzhou Municipal Science and Technology Program key projects

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference48 articles.

1. The relationship between different dimensions of alcohol use and the burden of disease—an update

2. Reporting about Alcohol: A Guide for Journalists; World Health Organization, 2023; https://www.who.int/publications/i/item/9789240071490 (accessed 2023-11-07).

3. Human alcohol-related neuropathology

4. Alcohol use disorders

5. Advances in the science and treatment of alcohol use disorder

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