Discovery of Dual Lysine Methyltransferase G9a and EZH2 Inhibitors with In Vivo Efficacy against Malignant Rhabdoid Tumor-Reference-Cited by-全球学者库

Discovery of Dual Lysine Methyltransferase G9a and EZH2 Inhibitors with In Vivo Efficacy against Malignant Rhabdoid Tumor

Published:2023-04-06 Issue:8 Volume:66 Page:5685-5702
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shi Yajie¹,Zhang Qiuyue²,Zhang Maoying¹,Chen Yongsong¹,Sun Jianwen¹,Chen Lu¹,Liu Sen²,Liu Zhongbo³,Yang Jingyu²,Wu Chunfu²,Zheng Zhonghui⁴,Wang Lihui²,Chen Guoliang¹^ORCID

Affiliation:

1. Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, P. R. China

2. Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, P. R. China

3. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, P. R. China

4. Shandong Xinhua Pharmaceutical Co., Ltd., Zibo 255086, P. R. China

Funder

Taishan Industry Leading Talents

People's Government of Liaoning Province

Liaoning Revitalization Talents Program

Natural Science Foundation of Shenyang City

Department of Education of Liaoning Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)