Non-covalent Small-Molecule Kelch-like ECH-Associated Protein 1–Nuclear Factor Erythroid 2-Related Factor 2 (Keap1–Nrf2) Inhibitors and Their Potential for Targeting Central Nervous System Diseases
Author:
Affiliation:
1. Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark
Funder
Drug Research Academy, K?benhavns Universitet
Lundbeckfonden
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00358
Reference90 articles.
1. Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers
2. Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options
3. Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis
4. Springer Series in Translational Stroke Research;Bach A.,2017
5. The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity
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