Discovery and Preclinical Development of IIIM-290, an Orally Active Potent Cyclin-Dependent Kinase Inhibitor-Reference-Cited by-同舟云学术

Discovery and Preclinical Development of IIIM-290, an Orally Active Potent Cyclin-Dependent Kinase Inhibitor

Published:2018-02-06 Issue:4 Volume:61 Page:1664-1687
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bharate Sandip B.¹²^ORCID,Kumar Vikas²³,Jain Shreyans K.⁴,Mintoo Mubashir J.²⁵,Guru Santosh K.⁵,Nuthakki Vijay K.¹,Sharma Mohit¹,Bharate Sonali S.³,Gandhi Sumit G.²⁶,Mondhe Dilip M.²⁵,Bhushan Shashi⁵⁷,Vishwakarma Ram A.¹²^ORCID

Affiliation:

1. Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu-180001, India

2. Academy of Scientific & Innovative Research, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu-180001, India

3. Preformulation Laboratory, PK−PD Toxicology & Formulation Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu-180001, India

4. Natural Products Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu-180001, India

5. Cancer Pharmacology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu-180001, India

6. Plant Biotechnology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu-180001, India

7. Indian Pharmacopeia Commission, Sec-23, Raj Nagar, Ghaziabad-201002, India

Funder

Council of Scientific and Industrial Research

University Grants Commission

Department of Biotechnology , Ministry of Science and Technology

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01765

Reference62 articles.

1. Cell-Cycle Therapeutics Come of Age

2. Emerging cell cycle inhibitors for acute myeloid leukemia

3. Cyclin-dependent protein kinase inhibitors including palbociclib as anticancer drugs

4. Palbociclib improves survival in advanced breast cancer

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