Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development
Author:
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01346
Reference54 articles.
1. Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2. Genome maintenance mechanisms for preventing cancer
3. Perspective on the Pipeline of Drugs Being Developed with Modulation of DNA Damage as a Target
4. A comprehensive look of poly(ADP-ribose) polymerase inhibition strategies and future directions for cancer therapy
5. Review of Poly (ADP-ribose) Polymerase (PARP) Mechanisms of Action and Rationale for Targeting in Cancer and Other Diseases
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