Folic Acid–Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting-Reference-Cited by-同舟云学术

Folic Acid–Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting

Published:2021-03-12 Issue:6 Volume:64 Page:3204-3221
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Marverti Gaetano¹,Marraccini Chiara²,Martello Andrea¹,D’Arca Domenico¹,Pacifico Salvatore³,Guerrini Remo³,Spyrakis Francesca²^ORCID,Gozzi Gaia¹,Lauriola Angela¹,Santucci Matteo²,Cannazza Giuseppe²^ORCID,Tagliazucchi Lorenzo²,Cazzato Addolorata Stefania²,Losi Lorena²,Ferrari Stefania²,Ponterini Glauco²,Costi Maria P.²^ORCID

Affiliation:

1. Department Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena, Italy

2. Department Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy

3. Department of Chemical and Pharmaceutical Sciences, University of Ferrara, Via Fossato di Mortara, 44121 Ferrara, Italy

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c02107