Host Defense Peptide-Mimicking Amphiphilic β-Peptide Polymer (Bu:DM) Exhibiting Anti-Biofilm, Immunomodulatory, and in Vivo Anti-Infective Activity

Author:

Etayash Hashem1ORCID,Qian Yuxin2ORCID,Pletzer Daniel13ORCID,Zhang Qiang4ORCID,Xie Jiayang2ORCID,Cui Ruxin2,Dai Chengzhi2ORCID,Ma Pengcheng2ORCID,Qi Fan2ORCID,Liu Runhui24ORCID,Hancock Robert E. W.1

Affiliation:

1. Centre for Microbial Diseases and Immunity Research, Department of Microbiology and Immunology, University of British Columbia, 2259 Lower Mall Research Station, Vancouver, British Columbia V6T 1Z4, Canada

2. State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China

3. Department of Microbiology and Immunology, University of Otago, 720 Cumberland Street, Dunedin 9054, New Zealand

4. Key Laboratory for Ultrafine Materials of Ministry of Education, Research Center for Biomedical Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China

Funder

Natural Science Foundation of Shanghai

Canadian Institutes of Health Research

Ministry of Education of the People's Republic of China

Ministry of Science and Technology of the People's Republic of China

Killam Trusts

Cystic Fibrosis Canada

Canada Research Chairs

State Key Laboratory of Bioreactor Engineering

National Natural Science Foundation of China

Michael Smith Foundation for Health Research

University of British Columbia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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