Discovery of Selective Small-Molecule Inhibitors for the β-Catenin/T-Cell Factor Protein–Protein Interaction through the Optimization of the Acyl Hydrazone Moiety-Reference-Cited by-同舟云学术

Discovery of Selective Small-Molecule Inhibitors for the β-Catenin/T-Cell Factor Protein–Protein Interaction through the Optimization of the Acyl Hydrazone Moiety

Published:2015-05-22 Issue:11 Volume:58 Page:4678-4692
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Catrow J. Leon¹,Zhang Yongqiang¹,Zhang Min¹,Ji Haitao¹

Affiliation:

1. Department of Chemistry, Center for Cell and Genome Science, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112−0850, United States

Funder

Pulmonary Fibrosis Foundation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00223

Reference84 articles.

1. Dynamic combinatorial libraries of pseudo-peptide hydrazone macrocycles

2. Direct screening of a dynamic combinatorial library using mass spectrometry

3. Nucleophilic catalysis of acylhydrazone equilibration for protein-directed dynamic covalent chemistry