How Beyond Rule of 5 Drugs and Clinical Candidates Bind to Their Targets
Author:
Affiliation:
1. Department of Chemistry—BMC, Uppsala University, Box 576, SE-751 23 Uppsala, Sweden
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01286
Reference59 articles.
1. Trends in the exploitation of novel drug targets
2. Getting pharmaceutical R&D back on target
3. Target selection for FDA-approved medicines
4. Diagnosing the decline in pharmaceutical R&D efficiency
5. Clinical development success rates for investigational drugs
Cited by 257 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. DrugSynthMC: An Atom-Based Generation of Drug-like Molecules with Monte Carlo Search;Journal of Chemical Information and Modeling;2024-09-09
2. The Influence of Disulfide, Thioacetal and Lanthionine‐Bridges on the Conformation of a Macrocyclic Peptide;Chemistry – A European Journal;2024-08-20
3. Small Natural Cyclic Peptides from DBAASP Database;Pharmaceuticals;2024-06-27
4. Exploring SureChEMBL from a drug discovery perspective;Scientific Data;2024-05-16
5. Metabolism-driven in vitro/in vivo disconnect of an oral ERɑ VHL-PROTAC;Communications Biology;2024-05-13
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3