Targeting the Epidermal Growth Factor Receptor with Molecular Degraders: State-of-the-Art and Future Opportunities

Author:

Maity Pritam1,Chatterjee Joydeep1,Patil Kiran T.1,Arora Sahil1,Katiyar Madhurendra K.1,Kumar Manvendra1ORCID,Samarbakhsh Amirreza2,Joshi Gaurav3ORCID,Bhutani Priyadeep4,Chugh Manoj5,Gavande Navnath S.26,Kumar Raj1ORCID

Affiliation:

1. Laboratory for Drug Design and Synthesis, Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, 151401 Bathinda, India

2. Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan 48201, United States

3. Department of Pharmaceutical Science, Hemvati Nandan Bahuguna Garhwal (A Central) University, Srinagar 246174, Dist. Garhwal (Uttarakhand), India

4. Jubilant Biosys Limited, 560022 Bangalore, India

5. In Vitro Diagnostics, Transasia BioMedical Pvt. Ltd. 400072 Mumbai, India

6. Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, Michigan 48201, United States

Funder

Indian Council of Medical Research

Council of Scientific and Industrial Research, India

DMC Foundation

Bristol-Myers Squibb

U.S. Department of Defense

Wayne State University

National Institutes of Health

Michigan SPORE

Richard Barber Interdisciplinary Research Program

VA

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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