Exploiting Structural Dynamics To Design Open-Flap Inhibitors of Malarial Aspartic Proteases
Author:
Affiliation:
1. Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV1006, Latvia
Funder
European Commission
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00184
Reference119 articles.
1. Global Report on Insecticide Resistance in Malaria Vectors: 2010–2016; World Health Organisation (WHO), 2018.
2. Artemisinin Resistance inPlasmodium falciparumMalaria
3. Drug-resistant malaria − an insight
4. Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway.
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