The Blood–Brain Barrier (BBB) Score
Author:
Affiliation:
1. Krembil Research Institute, University Health Network, 60 Leonard Avenue, Toronto M5T 2S8, Canada
2. Department of Medicine, University of Toronto, Toronto M5G 2C4, Canada
3. Department of Chemistry, University of Toronto, Toronto M55 3H6, Canada
Funder
Canada Research Chairs
Krembil Foundation
Publisher
American Chemical Society (ACS)
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01220
Reference33 articles.
1. Structure and function of the blood–brain barrier
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3. Securing the future of drug discovery for central nervous system disorders
4. An analysis of the attrition of drug candidates from four major pharmaceutical companies
5. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
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