4D-Printed Dynamic Materials in Biomedical Applications: Chemistry, Challenges, and Their Future Perspectives in the Clinical Sector

Author:

Zhou Wenxian1,Qiao Zhiguang23,Nazarzadeh Zare Ehsan4ORCID,Huang Jinfeng1,Zheng Xuanqi1,Sun Xiaolei5,Shao Minmin6,Wang Hui1,Wang Xiaoyan7,Chen Dong1,Zheng Jing8,Fang Shan9,Li Yan Michael10,Zhang Xiaolei1ORCID,Yang Lei1,Makvandi Pooyan111213ORCID,Wu Aimin1

Affiliation:

1. Department of Orthopaedics, Bioprinting Research Group, Zhejiang Provincial Key Laboratory of Orthopaedics, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, China

2. Medical 3D Printing Center, Shanghai Jiaotong University, Shanghai 200011, China

3. Department of Orthopaedics, Shanghai Key Laboratory of Orthopaedic Implants, Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China

4. School of Chemistry, Damghan University, Damghan 36716-41167, Iran

5. Department of Orthopaedics, Tianjin Hospital, Tianjin 300210, China

6. Department of ENT and Neck Surgery, Wenzhou Center Hospital, Dingli Hospital of Wenzhou Medical University, Wenzhou Institute of Medical Sciences, Wenzhou 325000, China

7. Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China

8. Engineering Research Center of Clinical Functional Materials and Diagnosis & Treatment Devices of Zhejiang Province, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325000, China

9. Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200050, China

10. Department of Neurosurgery and Oncology, University of Rochester Medical Center, School of Medicine and Dentistry, Rochester, New York 14642, United States

11. Institute for Polymers, Composites and Biomaterials, National Research Council, IPCB-CNR, Naples 80125, Italy

12. Chemistry Department, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz 61537-53843, Iran

13. Department of Medical Nanotechnology, Faculty of Advanced Technology in Medicine, Iran University of Medical Sciences, Tehran 14496-14535, Iran

Funder

Wenzhou Municipal Science and Technology Bureau

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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