Gaining Insight into Off-Target Mediated Effects of Drug Candidates with a Comprehensive Systems Chemical Biology Analysis-Reference-Cited by-同舟云学术

Gaining Insight into Off-Target Mediated Effects of Drug Candidates with a Comprehensive Systems Chemical Biology Analysis

Published:2009-01-13 Issue:2 Volume:49 Page:308-317
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Scheiber Josef¹,Chen Bin¹,Milik Mariusz¹,Sukuru Sai Chetan K.¹,Bender Andreas¹,Mikhailov Dmitri¹,Whitebread Steven¹,Hamon Jacques¹,Azzaoui Kamal¹,Urban Laszlo¹,Glick Meir¹,Davies John W.¹,Jenkins Jeremy L.¹

Affiliation:

1. Lead Discovery Informatics and Preclinical Safety Profiling, CPC, Novartis Institutes for Biomedical Research, 250 Massachussetts Avenue, Cambridge, Massachusetts 02139, and Preclinical Safety Profiling and Molecular Libraries Informatics, CPC, Novartis Pharma AG, Forum 1, 4002 Basel, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci800344p

Reference71 articles.

1. When good drugs go bad

2. Drug-Related Deaths

3. Adverse Drug Reaction-Related Hospitalisations

4. Vaccine partnerships to tackle neglected diseases

5. Keynote review: In vitro safety pharmacology profiling: an essential tool for successful drug development

Cited by 142 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Drugging the entire human proteome: Are we there yet?;Drug Discovery Today;2024-03

2. Exposure to the Natural Compound Climacostol Induces Cell Damage and Oxidative Stress in the Fruit Fly Drosophila melanogaster;Toxics;2024-01-24

3. Pretrained transformer models for predicting the withdrawal of drugs from the market;Bioinformatics;2023-08-01

4. Accelerated NLRP3 inflammasome-inhibitory peptide design using a recurrent neural network model and molecular dynamics simulations;Computational and Structural Biotechnology Journal;2023

5. Predicting adverse drug effects: A heterogeneous graph convolution network with a multi-layer perceptron approach;PLOS ONE;2022-12-14