Quinazolinone–Hydrazine Cyanoacetamide Hybrids as Potent Multitarget-Directed Druggable Therapeutics against Alzheimer’s Disease: Design, Synthesis, and Biochemical, In Silico, and Mechanistic Analyses-Reference-Cited by-同舟云学术

Quinazolinone–Hydrazine Cyanoacetamide Hybrids as Potent Multitarget-Directed Druggable Therapeutics against Alzheimer’s Disease: Design, Synthesis, and Biochemical, In Silico, and Mechanistic Analyses

Published:2024-09-05 Issue: Volume: Page:
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Yelamanda Rao Kandrakonda¹,Chandran Remya²,Dileep K. V.²,Gorantla Sri Charitha³,Jeelan Basha Shaik¹⁴,Mothukuru Sreelakshmi¹,Siva kumar Irla⁵,Vamsi Katta⁶,Kumar Sandeep⁵⁷^ORCID,Reddy Aramati Bindu Madhava³,Subramanyam Rajagopal⁸,Damu Amooru Gangaiah¹^ORCID

Affiliation:

1. Bioorganic Chemistry Research Laboratory, Department of Chemistry, Yogi Vemana University, Kadapa, Andhra Pradesh 516005, India

2. Laboratory for Computational and Structural Biology, Jubilee Centre for Medical Research, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala 680005, India

3. Department of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana 500046, India

4. Department of Chemistry, Santhiram Engineering College (Autonomous), Nandyal, Andhra Pradesh 518501, India

5. Soft Condensed Matter, Raman Research Institute, CV Raman Avenue, Sadashiva Nagar, Bangalore 560080, India

6. Department of Chemistry, Indian Institute of Science and Education Research (IISER), Tirupati, Andhra Pradesh 517507, India

7. Nitte Meenakshi Institute of Technology, Yelahanka, Bangalore 560064, India

8. Department of Plant Sciences, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana 500046, India

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.4c00424

Reference65 articles.

1. Alzheimer's disease

2. Alzheimer's disease: Recent treatment strategies

3. Current drug targets for Alzheimer's disease treatment

4. Alzheimer's Disease

5. World Population Prospects 2022: Summary of Results|Population Division. https://www.un.org/development/desa/pd/content/World-Population-Prospects-2022 (accessed Dec 12, 2023).