Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers

Author:

Mannini Benedetta1ORCID,Vecchi Giulia1,Labrador-Garrido Adahir23,Fabre Bertrand4,Fani Giulia15,Franco Jaime M.23,Lilley Kathryn4,Pozo David23,Vendruscolo Michele1ORCID,Chiti Fabrizio5ORCID,Dobson Christopher M.1,Roodveldt Cintia23ORCID

Affiliation:

1. Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, U.K.

2. Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER) - Universidad de Sevilla, Consejo Superior de Investigaciones Científicas (CSIC), Universidad Pablo de Olavide, 41092 Seville, Spain

3. Department of Medical Biochemistry, Molecular Biology and Immunology, University of Seville, 41092 Seville, Spain

4. Cambridge Centre for Proteomics, Systems Biology Centre, Department of Biochemistry, University of Cambridge, CB2 1GA Cambridge, U.K.

5. Department of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, 50134 Florence, Italy

Funder

Ministerio de Econom?a y Competitividad

Universidad de Sevilla

European Molecular Biology Organization

Italian Society of Biochemistry and Molecular Biology

Regional Ministry of Economy

Programa Ram?n y Cajal

Cambridge Centre for Misfolding Diseases

Programa Atracci?n de Talento

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

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