Identification of a Novel Oleic Acid Analog with Protective Effects in Multiple Cellular Models of Friedreich Ataxia-Reference-Cited by-同舟云学术

Identification of a Novel Oleic Acid Analog with Protective Effects in Multiple Cellular Models of Friedreich Ataxia

Published:2020-08-11 Issue:17 Volume:11 Page:2535-2542
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Cotticelli M. Grazia¹²,Forestieri Roberto³,Xia Shujuan¹²,Joyasawal Sipak⁴^ORCID,Lee Taehee¹²,Xu Kexin⁴,Smith III Amos B.³^ORCID,Huryn Donna M.³⁴^ORCID,Wilson Robert B.¹²⁵

Affiliation:

1. Department of Pathology and Laboratory Medicine, Children’s Hospital Philadelphia, Philadelphia, Pennsylvania 19104, United States

2. The Penn Medicine/CHOP Center of Excellence for Friedreich’s Ataxia Research, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

3. Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

4. Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, United States

5. Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

Funder

University of Pittsburgh

Friedreich's Ataxia Research Alliance

Hamilton and Finneran Families

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.0c00323

Reference22 articles.

1. Clinical and Genetic Abnormalities in Patients with Friedreich's Ataxia

2. Friedreich's Ataxia: Autosomal Recessive Disease Caused by an Intronic GAA Triplet Repeat Expansion

3. Small molecules affecting transcription in Friedreich ataxia

4. Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin

5. MMS19 Assembles Iron-Sulfur Proteins Required for DNA Metabolism and Genomic Integrity

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